GERD and Nexium Treatment

Gastroesophageal reflux disease (GERD) is often mistakenly considered with stomach ulcer, still this disorder is characterized by the persistent reflow of the ingested food from the stomach through the esophagus back to the oral cavity.

This reflow of the food leads to irritation and creates pain and disturbance in the esophagus. The common symptoms of GERD are:

 heartburn;

 burning pain in the chest;

 feeling of nausea after meals;

 coughing, wheezing, difficulty breathing;

 trouble in swallowing;

 rough voice;

 soar throat.

Gastroesophageal reflux disease can occur due to dysfunction of the muscle ring called esophageal sphincter that does not close tight and does not prevent the food from the stomach enter the esophagus.

Certain other conditions can result in GERD including obesity, smoking and alcohol abuse. Pregnant women can also be more prone to this disorder.

Gastroesophageal reflux disease is diagnosed with the help of certain tests and procedures. One of the most common is esophagogastroduodenoscopy involving the usage of a special camera that enters the gastrointestinal tract and shows the problem from the inside. Other methods used are: measuring of the pH of the esophagus contents, esophageal manometry.

Actually the treatment is adjusted by a specialist who makes a diagnosis of GERD. The program of GERD treatment is using special medicines and diet. Avoiding food which can induce the reflux is very important. Alcohol, smoking and caffeine should also be omitted.

Nexium can be prescribed to cope with the disease. It works to prevent the acidity coming from the stomach. During the clinical studies of this medicine use in children and adult patients, the results reported were significant improvement in the GERD condition.

Nexium should be taken as prescribed by a specialist. The duration of the treatment is usually 4-8 weeks. In some cases the duration can be longer after evaluation of a doctor.

Nexium interactions with other medicines

The proper use of any medicine helps to avoid any serious risks to your health, side effects and unwanted effects related to the application of this medicine. Before using any medicine including Nexium it is advised to visit a doctor for consultation and discuss possible drug interactions with this remedy.

Nexium is from the class of proton pump inhibitors potent to decrease the acid release and its amount in the stomach. This medicine is widely prescribed for the curing of the following conditions reflux disorder or so called GERD (gastroesophageal reflux disease), Zollinger –Ellison syndrome and other conditions characterized by the symptom of extra acidity.

The medication Nexium is produced in convenient forms of capsules, powder for oral solution and injection.


The interactions of Nexium with other medicines are possible, especially if this medicine is used with the listed below drugs. There are some commonly used or prescribed combinations related to Nexium. So, it is needed to inform your doctor if you use any of the following:

  • cilostazol (Pletal);
  • citalopram (Celexa);
  • clopidogrel (Plavix);
  • dexamethasone (Cortastat);
  • diazepam (Valium);
  • digoxin (Lanoxin);
  • methotrexate (Rheumatrex, Trexall);
  • rifampin (Rifadin, Rifater, Rifamate);
  • Atazanavir (Reyataz);
  • Nelfinavir (Viracept);
  • Any medicines prescribed to treat HIV or AIDS including etravirine (Intelence), rilpivirine (Complera, Edurant), or saquinavir (Invirase);
  • tacrolimus (Prograf);
  • voriconazole (Vfend).
  • The listed medicines should be avoided or excluded from your treatment regime. Among the other things which should be eliminated, there are alcohol use and other restrictions you will get from your doctor.

    The improvement of your condition depends on the correctness of Nexium application and avoidance of restricted or limited things.

    Nexium side effects

    нексиEsomeprazole, the main component of Nexium is designed to treat specific stomach and esophagus disorders including acid reflux and ulcers. This medicine manages these conditions by significant reduction of the amount of acid presenting in the stomach. Nexium manages heartburn, helps in case when a patient cannot swallow, and prevents stable cough which often occurs with the stomach acid problem. By helping in controlling the acid production in the stomach and esophagus, Nexium is able to prevent ulcers. Besides, it was proven that this medicine is very effective in preventing cancer of the esophagus. Nexium is generally well tolerated by most patients. Still along with its required effects, it may cause some undesirable ill effects. Some of these side effects may be dangerous and, if they occur they need special medical attention.нек Serious side effects are: • Severe allergic reactions to Nexium; • Dizziness; • Confusion; • Muscle movements; • Seizure; • Heart beat that is fast or uneven. These side effects require immediate doctor’s attention. In case any of the serious side effects occurs, a person should call medical help. нексMore common side effects of Nexium include: • Headache; • Drowsiness; • Diarrhea; • Stomach pain; • Constipation; • Dry mouth. A patient should be watchful for the effects which Nexium may produce in him/her. If necessary the medicine should be immediately stopped. A professional medical consultation may be needed in case a person suspects that his/her side effects are caused by using Nexium.

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